Since effective collaboration cannot be enforced but requires all parties wanting to work together, it is worth noting that a large proportion of the ITFoM partners already have a proven collaboration track record from previous and on-going EU and otherwise funded projects.
A small number of selected large-scale projects merit extra mention in this context. ITFoM participants collaborate in large international projects like the 1000 Genomes Project (Sanger, EMBL-EBI, MPG), ICGC - the International Cancer Genome Consortium (OICR, MPG, EMBL-EBI, CNAG, Sanger, CEA, DKFZ, UIO, CCCC, KI), IHEC - the International Human Epigenome Project (UCL, CNIO, EMBL, Sanger, MPG, CNAG, ONT, INSERM, UEDIN, UNICO, UNIGE, BSC); in various Innovative Medicine Initiative (IMI) projects like EHR4CR - Electronic Health Records Systems for Clinical Research (EMBL, INSERM, UCL, UNIGE, UNIMAN, WWUM, UNIGL, UEDIN, BAY, SA, and Janssen), Oncotrack - Methods for systematic next generation oncology biomarker development (MPG, BAY, MUG, UU, UCL, IPRI, ATG, CCCC, Janssen, Roche); in large infrastructure projects under the European Strategy Forum for Research Infrastructures (ESFRI), ELIXIR - Life Science Infrastructure for Biological information (EMBL-EBI, Sanger, CNIO), BBMRI - Biobanking and Biomolecular Resources Research Infrastructure (MUG, IPRI, MPG, KI, INSERM, UNIMAN, EGCUT, TIGEM, IBMT, CU, AAU, IMER, UMCG), EATRIS (UNICO, DKFZ, ISS, UIO), ISBE - Infrastructure for Systems Biology Europe (UNIMAN, UvA, DKFZ, ICL, MDC, VUA, UNILJ, EMBL-EBI), ESGI – European Sequencing and Genotyping Infrastructure (MPG, Sanger, EMBL, CEA, INSERM, UU, MUG), BioMedBridges (EMBL-EBI, KI, VUA, INSERM, UNICO, MUG); in technology development projects such as READNA - Revolutionary Approaches and Devices for Nucleic Acid analysis (CNAG, MPG, ONT, UU, ULEIC); and in computing projects such as PRACE - Partnership for Advanced Computing in Europe (VŠB, BSC, CSC, PSNC, UNILJ, ETH). In addition to PRACE, various members are already involved with the most important international and European HPC/Exascale initiatives like IESP, the EESI-2 project, the new European technology platform for HPC (ETP4HPC), the European Grid Initiative (EGI), and the US Government Exascale activities.
These initiatives have all identified life sciences and health as key applications for exascale. ITFoM will take a lead in the definition of application requirements and the implementation of solutions for the exascale era. In particular ITFoM will address many of the topics outlined in the EESI report on life sciences and health. Last, but not least, the VPH Institute represents 67 of the most important institutions that collaborated in the dozens of European and international projects funded under the heading of Virtual Physiological Human.
These already established connections are expected to bloom into even larger interdisciplinary synergies and spread to encompass international collaborations. ITFoM intends to be as inclusive as possible with respect to associated partners and also envisions additional full partners to join the consortium during the lifetime of the project.