Korea Advanced Institute of Science and Technology, KAIST
Korea Advanced Institute of Science and Technology (KAIST) is the first research-oriented science and technology university in Korea. KAIST has College of Life Science and Bioengineering, which comprises two departments and one school, Department of Bio and Brain Engineering, Department of Biological Sciences, and Graduate School of Medical Science and Engineering. It also operates Pappalardo Medical Center. KAIST pursues multidisciplinary education and research in the fields of bioscience, biotechnology, and bioengineering. Its goal is to support the nation’s endeavor to advance bioscience, biotechnology, and bioengineering through education, research and development. New areas of fusion bioscience and bioengineering are also emphasized through convergence of information technology and nanotechnology
KAIST has well-established background to pursue the ITFoM research as follows: Dept. of Bio and Brain Engineering has strong bioinformatics and systems biology expertise including bio-network inference, biomarker discovery, system modeling, and network dynamics analysis. Graduate School of Medical Science and Engineering has rich human resources mainly trained in medical schools, and focusing of immunology. Dept. of Biological sciences has very well-established experimental science resources encompassing biochemistry to animal studies. Pappalardo Medical Center has 13 clinical divisions and active research-oriented facilities.
Profile of staff members
Doheon Lee is the head of Dept. of Bio and Brain Engineering, and a leading expert in bioinformatics. His major research interests include multi-level, multi-scale, bio-system modeling and bio-data mining. Sang-Yup Lee is the dean of College of Life Science and Bioengineering, and an internationally renowned expert in systems biology and metabolic engineering.
Five recent publications relevant to the project
1) Eunjoon Kim et al. (2011, Nature medicine) GIT1 is associated with attention deficit/hyperactivity disorder (ADHD) and ADHD-like behaviors in mice
2) Sang-Yup Lee et al. (2011 Molecular Systems Biology) Integrative genome-scale metabolic analysis of Vibrio vulnificus for drug targeting and discovery", Molecular systems biology
3) Doheon Lee et al. (2010 Bioinformatics) PSExplorer: Whole parameter space exploration for molecular signaling pathway dynamics
4) Joonho Choe et al. (2010, Nature) The novel gene twenty-four defines a critical translational step in the Drosophila clock
5) Doheon Lee et al. (2007 BMC Bioinformatics) BioCAD: An information fusion platform for bio-network inference and analysis